2007 Program Schedule

Thursday, October 11, 2007

7:00pm: Registration

Friday, October 12, 2007

8:00 AM - 10:00 AM

Session 1: Lipid Oxidation, Inflammation, and Vascular Disease

Moderator: Norbert Leitinger, University of Virginia

8:00-8:30 AM- Norbert Leitinger, University of Virginia

“Oxidation, Inflammation, and Vascular Disease”

8:30-9:00 AM- Suzanne Barbour, Virginia Commonwealth University

“Lp-PLA2/PAF-AH Regulation”

 

9:00-9:30 AM- Aimee Landar, University of Alabama-Birmingham

“Protein Modification by Oxidized Lipids”

 

9:30-9:45 AM- Jody Ullery, Vanderbilt University Medical Center

"Triglyceride Enrichment Alters Cholesterol Metabolism and ER Stress in Macrophage Foam Cells"

 

9:45-10:00 AM- Samar Hammad, Medical University of South Carolina

“Intracellular trafficking of free oxidized LDL and oxidized LDL immune complexes in macrophages”

10:00 AM - 10:30 AM

BREAK

10:30 AM - 12:30 AM

Session 2: Cellular Lipid Metabolism

Moderator:  Nobuyo Maeda, University of North Carolina-Chapel Hill

 

10:30-11:00 AM- Mike Altenburg, University of North Carolina-Chapel Hill

“Human ApoE Isoforms and VLDL Clearance”

 

11:00- 11:30 AM- Mark Brown, Wake Forest University School of Medicine

“Role of CGI-58 in Hepatic Lipid Mobilization and Secretion”

 

11:30- 12:00 AM- Shadab A. Siddiqi, University of Tennessee Health Sciences Center-Memphis

“VLDL-transporting-vesicle (VTV): A New Member of the ER-derived Vesicle Family”

 

12:00- 12:30 AM- Larry Swift, Vanderbilt University Medical Center

“Microsomal Triglyceride Transfer Protein:  Another Lipid Droplet Protein?”

 

AFTERNOON FREE

7:00 PM - 9:00 PM 

Session 3: Steps in Chylomicron Formation and Export from the ER

Moderator: Charles Mansbach, University of Tennessee Health Sciences Center-Memphis

7:00- 7:30 PM- Dennis Black, University of Tennessee Health Sciences Center-Memphis

“Role of apo A-IV in Neonatal Lipid Absorption”

 

7:30- 8:00 PM- Mahmood Hussain, SUNY- Downstate Medical Center

"Regulation of MTP and intestinal lipoprotein assembly".

 

8:00- 8:30 PM- Charles Mansbach, University of Tennessee Health Sciences Center-Memphis

“The Regulation of Budding of the Pre-chylomicron Transport Vesicle from Intestinal ER”

 

8:30- 9:00 PM- Rosalind Coleman, University of North Carolina-Chapel Hill

“Why Do We Need 4 (+?) Enzymes to Initiate Triacylglycerol Synthesis?”

Saturday, October 13, 2007

8:00 AM - 10:00 AM

Session 4: Diabetes, Metabolic Syndrome and Adipocyte Biology

Moderator:  Alyssa Hasty, Vanderbilt University Medical Center

8:00- 8:30 AM- Lisa Tannock, University of Kentucky

“Diabetes, Obesity, and Inflammation: a Clinical Perspective”

8:30- 9:00 AM- Ron F. Morrison, University of North Carolina -Greensboro

“Ubiquitin E3 Ligases in Targeted Protein Degradation during Adipocyte Hyperplasia”

9:00- 9:30 AM- Marshall (Barney) Elam, University of Tennessee Health Sciences Center

“Transcriptional and Posttranscriptional Regulation of SREBP-1c by Insulin”

9:30- 9:45 AM- Jerod Denton, Vanderbilt University Medical Center

“Accumulation of Adipocyte Triglyceride Triggers ER stress in Macrophages”

9:45- 10:00 AM- Saraswathi Viswanathan, Vanderbilt University Medical Center

“Accumulation of Intracellular Free Fatty Acids Induces a Pro-inflammatory Response and Apoptosis in Macrophages”

 

10:00 AM - 10:30 AM

BREAK

10:30 AM - 12:30 AM

Session 5: HDL Structure and Function

Moderator: Ling Li, University of Alabama at Birmingham

10:30- 10:50 AM- Ling Li, University of Alabama at Birmingham

“HDL Dynamics: Assembly and Structural Plasticity of ApoA-I-Phospholipid Complexes”

 

10:50- 11:15 AM- James Patterson, University of Alabama at Birmingham

“Computational Simulations of Model ApoA-I:Lipid Complexes”

 

11:15- 11:40 AM- Yan Ru Su, Vanderbilt University Medical Center

“The effects of ApoA-I and ApoA-I Milano Variant on Macrophage Cholesterol Efflux and Atherosclerosis”

 

11:40- 12:05 AM- John S. Parks, Wake Forest University Health Science

“Pre-beta HDL Formation and Metabolism”

 

12:05- 12:30 AM- Hong Wang, Temple University

“Hyperhomocysteinemia with HDL Metabolism”

_______________________________

6:00 PM - 7:00 PM

Saturday Evening Keynote Address

Dr. Ira Tabas, Columbia University

"Macrophage Death in Advanced Atherosclerosis"

______________________________

Sunday, October 14, 2007

8:00 AM - 10:00 AM

Session 6: what are future targets for treatment among the apoB containing lipoproteins?

Moderator: Virgil Brown, Emory University

8:00- 8:30 AM- Peter W. F. Wilson,  Emory University

“Lipid Assessment is Adequate”

 

8:30- 9:00 AM- W. Virgil Brown, Emory University

“Apolipoproteins hold Promise as Targets

 

9:00- 9:30 AM- Jim Otvos, LipoScience, Inc.

“LDL particle number may be the best treatment target”

 

9:30- 10:00 AM- Nhoc-Anh Le, Emory University

“Post-challenge Changes in Risk Assessment”

10:00 AM - 10:30 AM

BREAK

10:30 AM - 12:30 AM

Session 7: Immunity, lipids, and vascular disease: closing the gap

Moderator: Amy Major, Vanderbilt University Medical Center

10:30-11:00 AM- Nilamadhab Mishra, Wake Forest University Health Sciences

“Histone Deacetylases at the Crossroads of Inflammation and Lipid Metabolism”

 

11:00- 11:30 AM- Cornelia Weyand, Emory University

Immune Activation in the Atherosclerotic Plaque” 

 

11:30- 11:50 AM- Vicki King, University of Kentucky

“Interferon-g and the Interferon-Inducible Chemokine, CXCL10 Have Discordant Effects of Atherosclerosis and Aneurysm Formation”

 

11:50- 12:10 AM- Janusz Kabarowski, University of Alabama-Birmingham

“Modulation of Lipoprotein metabolism and Atherosclerosis by the G2A Receptor”

 

12:10- 12:30 AM- Todd Hulgan, Vanderbilt University Medical Center

“Dyslipidemia, Oxidant Stress, and Cardiovascular Disease during HIV Therapy”